A novel 2:1 cycloadduct of dimethyl acetylenedicarboxylate with 3,5-diphenyl-4-methoximino-4H-pyrazole 1,2-dioxide

Authors

Andre L. Kilpatrick, Illinois State University
Kalyan Nagulapalli, Illinois State University
Joel M. Esken, Illinois State University
Gregory M. Ferrence, Illinois State University
John F. Hansen, Illinois State University

Document Type

Article

Publication Title

Tetrahedron Letters

Abstract

Two equivalents of dimethyl acetylenedicarboxylate react with 3,5-diphenyl-4-methoximino-4H-pyrazole 1,2-dioxide in acetonitrile under reflux. The major product was shown by X-ray analysis to be a 5,8-epoxyisoxazolo[2,3-d]-[1,4]-diazepine derivative. © 2003 Elsevier Science Ltd. All rights reserved.

First Page

3789

Last Page

3791

DOI

10.1016/S0040-4039(03)00781-0

Publication Date

5-5-2003

Recommended Citation

Kilpatrick, Andre L.; Nagulapalli, Kalyan; Esken, Joel M.; Ferrence, Gregory M.; and Hansen, John F., "A novel 2:1 cycloadduct of dimethyl acetylenedicarboxylate with 3,5-diphenyl-4-methoximino-4H-pyrazole 1,2-dioxide" (2003). Pharmaceutical and Administrative Sciences Faculty Publications. 128. https://doi.org/10.1016/S0040-4039(03)00781-0
https://collections.uhsp.edu/pharm-admin-sciences_pubs/128