Appraising contemporary strategies to combat multidrug resistant gram-negative bacterial infections-proceedings and data from the gram-negative resistance summit
Document Type
Article
Publication Title
Clinical Infectious Diseases
Abstract
The emerging problem of antibiotic resistance, especially among Gram-negative bacteria (GNB), has become a serious threat to global public health. Very few new antibacterial classes with activity against antibiotic-resistant GNB have been brought to market. Renewed and growing attention to the development of novel compounds targeting antibiotic-resistant GNB, as well as a better understanding of strategies aimed at preventing the spread of resistant bacterial strains and preserving the efficacy of existing antibiotic agents, has occurred. The Gram-Negative Resistance Summit convened national opinion leaders for the purpose of analyzing current literature, epidemiologic trends, clinical trial data, therapeutic options, and treatment guidelines related to the management of antibiotic-resistant GNB infections. After an in-depth analysis, the Summit investigators were surveyed with regard to 4 clinical practice statements. The results then were compared with the same survey completed by 138 infectious disease and critical care physicians and are the basis of this article. © 2011 Author(s).
DOI
10.1093/cid/cir475
Publication Date
9-15-2011
Recommended Citation
Kollef, Marin H.; Golan, Yoav; Micek, Scott T.; Shorr, Andrew F.; and Restrepo, Marcos I., "Appraising contemporary strategies to combat multidrug resistant gram-negative bacterial infections-proceedings and data from the gram-negative resistance summit" (2011). Pharmacy Practice Faculty Publications. 109.
https://doi.org/10.1093/cid/cir475
https://collections.uhsp.edu/pharm-practice_pubs/109