Early appropriate empiric therapy and antimicrobial de-escalation
Document Type
Article
Publication Title
Antimicrobial Resistance: Problem Pathogens and Clinical Countermeasures
Abstract
Bacterial resistance to antibiotics creates a therapeutic challenge to clinicians when treating patients with a known or suspected infection. Increasing rates of resistance lead many clinicians to empirically treat patients with multiple broadspectrum antibiotics, which can perpetuate the cycle of increasing resistance and create an economic burden to society (see Chapter 4). Conversely, inappropriate initial therapy, defined as a regimen that lacks in vitro activity against an isolated organism, can lead to treatment failures that have negative patient outcomes.
First Page
231
Last Page
250
Publication Date
1-1-2007
Recommended Citation
Hollands, James M.; Micek, Scott T.; McKinnon, Peggy S.; and Kollef, Marin H., "Early appropriate empiric therapy and antimicrobial de-escalation" (2007). Pharmacy Practice Faculty Publications. 164.
https://collections.uhsp.edu/pharm-practice_pubs/164