A novel and efficient one-pot strategy for the synthesis of 1,2,4-triazoles: access to synthesis of penipanoid A and its analogues

Authors

A. Satyanarayana Reddy, Aragen Life Sciences Pvt. Ltd
V. Krishna Reddy, Aragen Life Sciences Pvt. Ltd
G. Nageswara Rao, Andhra University
K. Basavaiah, Andhra University
Kalyan C. Nagulapalli Venkata, University of Health Sciences and Pharmacy

Document Type

Article

Publication Title

RSC Advances

Abstract

We developed a novel one-pot strategy for synthesizing biologically important 1,2,4-triazole motifs from easily accessible 4-hydroxy phenylacetic acid, formamidine hydrochloride and hydrazine derivatives under mild conditions. This strategy enabled us to synthesize the natural penipanoid A and its analogues in one step.

First Page

2680

Last Page

2682

DOI

10.1039/d2ra06341g

Publication Date

1-18-2023

Recommended Citation

Reddy, A. Satyanarayana; Reddy, V. Krishna; Rao, G. Nageswara; Basavaiah, K.; and Nagulapalli Venkata, Kalyan C., "A novel and efficient one-pot strategy for the synthesis of 1,2,4-triazoles: access to synthesis of penipanoid A and its analogues" (2023). Pharmaceutical and Administrative Sciences Faculty Publications. 111. https://doi.org/10.1039/d2ra06341g
https://collections.uhsp.edu/pharm-admin-sciences_pubs/111