Dual functionalized janus nanocomposites for targeted pH-responsive drug delivery

Document Type

Conference Proceeding

Publication Title

Materials Research Society Symposium Proceedings

Abstract

A superparamagnetic Janus nanocomposite (SJNC) of polystyrene/Fe 3O4@SiO2 was designed and developed with dual surface bearing functional groups for medical diagnosis and treatment. Folic acid (FA) and doxorubicin (DOX) were conjugated stepwise to the surfaces. SJNCs were found to enable simultaneous cell-targeted drug delivery via pH-responsive release mechanism. Copyright © Materials Research Society 2014.

DOI

10.1557/opl.2014.216

Publication Date

1-1-2014

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