Self-assembling nanomicelles of a novel camptothecin prodrug engineered with a redox-responsive release mechanism

Authors

Xue Quan Li, Northwest University
Hui Yun Wen, Tongji University
Hai Qing Dong, Tongji University
Wei Ming Xue, Northwest University
Giovanni M. Pauletti, University of Cincinnati
Xiao Jun Cai, Tongji University
Wen Juan Xia, Tongji University
Donglu Shi, Tongji University
Yong Yong Li, Tongji University

Document Type

Article

Publication Title

Chemical Communications

Abstract

A novel amphiphilic camptothecin prodrug that spontaneously arranges into nanomicelles which preferentially release the cytotoxic drug under tumor-relevant reductive conditions is designed. © The Royal Society of Chemistry 2011.

First Page

8647

Last Page

8649

DOI

10.1039/c1cc12495a

Publication Date

8-14-2011

Recommended Citation

Li, Xue Quan; Wen, Hui Yun; Dong, Hai Qing; Xue, Wei Ming; Pauletti, Giovanni M.; Cai, Xiao Jun; Xia, Wen Juan; Shi, Donglu; and Li, Yong Yong, "Self-assembling nanomicelles of a novel camptothecin prodrug engineered with a redox-responsive release mechanism" (2011). Pharmaceutical and Administrative Sciences Faculty Publications. 165. https://doi.org/10.1039/c1cc12495a
https://collections.uhsp.edu/pharm-admin-sciences_pubs/165