Fine-needle aspiration of brown tumor of bone: Cytologic features with radiologic and histologic correlation

Document Type

Article

Publication Title

Diagnostic Cytopathology

Abstract

We report the case of a 40-year-old man with tertiary hyperparathyroidism due to end stage renal disease who initially presented with acute-onset paraplegia, elevated serum parathyroid hormone, and multiple bone abnormalities, including a large extradural intraspinal mass seen by magnetic resonance imaging. In contrast with imaging features, fine-needle aspiration cytology showed numerous benign-appearing multi-nucleated osteoclast-type giant cells that are the characteristics of either brown tumor or benign giant cell tumor of bone. Sheets of mononuclear spindled stromal cells were also noted. A core-needle biopsy confirmed the diagnostic features of brown tumor of hyperparathyroidism. © 2008 Wiley-Liss, Inc.

First Page

136

Last Page

139

DOI

10.1002/dc.20974

Publication Date

2-1-2009

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