Enaminones: Exploring additional therapeutic activities

Authors

Ivan O. Edafiogho, Kuwait University
Samuel B. Kombian, Kuwait University
Kethireddy V.V. Ananthalakshmi, Kuwait University
Noha N. Salama, Faculty of Pharmacy
Natalie D. Eddington, University of Maryland School of Pharmacy
Tiffany L. Wilson, Albany State University
Mariano S. Alexander, Howard University
Patrice L. Jackson, Howard University
Clive D. Hanson, Howard University
K. R. Scott, Howard University

Document Type

Article

Publication Title

Journal of Pharmaceutical Sciences

Abstract

Enaminones, enamines of β-dicarbonyl compounds, have been known for many years. Their early use has been relegated to serving as synthetic intermediates in organic synthesis and of late, in pharmaceutical development. Recently, the therapeutic potential of these entities has been realized. This review provides the background and current research in this area with emphasis of these agents as potential anticonvulsants, their proposed mechanisms of action, and as potential modulators of multidrug resistance (MDR). © 2007 Wiley-Liss, Inc. and the American Pharmacists Association.

First Page

2509

Last Page

2531

DOI

10.1002/jps.20967

Publication Date

1-1-2007

Recommended Citation

Edafiogho, Ivan O.; Kombian, Samuel B.; Ananthalakshmi, Kethireddy V.V.; Salama, Noha N.; Eddington, Natalie D.; Wilson, Tiffany L.; Alexander, Mariano S.; Jackson, Patrice L.; Hanson, Clive D.; and Scott, K. R., "Enaminones: Exploring additional therapeutic activities" (2007). Pharmaceutical and Administrative Sciences Faculty Publications. 249. https://doi.org/10.1002/jps.20967
https://collections.uhsp.edu/pharm-admin-sciences_pubs/249