Catalyst- and organic solvent-free synthesis of thioacids in water
Document Type
Article
Publication Title
Tetrahedron Letters
Abstract
Thioacids and thioamino acids were synthesized in excellent yields from readily available acyl benzotriazoles and sodium hydrosulfide in water at room temperature. The new methodology features mild reaction conditions, high yields, short reaction times, and does not involve the use of organic solvents or bases. The reaction is eco-friendly, and the workup procedure is simple and does not require chromatographic separation.
First Page
2018
Last Page
2021
DOI
10.1016/j.tetlet.2019.06.061
Publication Date
7-25-2019
Recommended Citation
Elagawany, Mohamed; Hegazy, Lamees; and Elgendy, B., "Catalyst- and organic solvent-free synthesis of thioacids in water" (2019). Pharmaceutical and Administrative Sciences Faculty Publications. 92.
https://doi.org/10.1016/j.tetlet.2019.06.061
https://collections.uhsp.edu/pharm-admin-sciences_pubs/92