A Cluster of Cefepime-induced Neutropenia during Outpatient Parenteral Antimicrobial Therapy

Authors

Kap Sum Foong, Washington University School of Medicine in St. Louis
Kevin Hsueh, Washington University School of Medicine in St. Louis
Thomas C. Bailey, Washington University School of Medicine in St. Louis
Lan Luong, BJC HealthCare
Ayesha Iqbal, BJC HealthCare
Christine Hoehner, BJC HealthCare
Lee Connor, Washington University School of Medicine in St. Louis
Ed Casabar, Barnes-Jewish Hospital
Michael Lane, Washington University School of Medicine in St. Louis
Yvonne Burnett, Washington University School of Medicine in St. Louis
David Ritchie, Barnes-Jewish Hospital
Tamara Krekel, Barnes-Jewish Hospital
Helen Newland, Barnes-Jewish Hospital
Lori Weilmuenster, BJC Home Care Services
Brett Heuring, BJC Home Care Services
Michael J. Durkin, Washington University School of Medicine in St. Louis
Yasir Hamad, Washington University School of Medicine in St. Louis

Document Type

Article

Publication Title

Clinical Infectious Diseases

Abstract

A cluster of cefepime-induced neutropenia (CIN) was identified from June 2017 to May 2018 in a regional outpatient parenteral antimicrobial therapy population. Our data suggest prolonged courses of cefepime (≥2 weeks), administered by rapid intravenous push, were associated with a higher risk of CIN.

First Page

534

Last Page

537

DOI

10.1093/cid/ciy1112

Publication Date

7-18-2019

Recommended Citation

Foong, Kap Sum; Hsueh, Kevin; Bailey, Thomas C.; Luong, Lan; Iqbal, Ayesha; Hoehner, Christine; Connor, Lee; Casabar, Ed; Lane, Michael; Burnett, Yvonne; Ritchie, David; Krekel, Tamara; Newland, Helen; Weilmuenster, Lori; Heuring, Brett; Durkin, Michael J.; and Hamad, Yasir, "A Cluster of Cefepime-induced Neutropenia during Outpatient Parenteral Antimicrobial Therapy" (2019). Pharmacy Practice Faculty Publications. 239. https://doi.org/10.1093/cid/ciy1112
https://collections.uhsp.edu/pharm-practice_pubs/239