Pharmacologic anticoagulation reversal in the emergency department
Document Type
Article
Publication Title
Advanced Emergency Nursing Journal
Abstract
Anticoagulation therapies are 1 of the most commonly encountered therapeutic areas by health care professionals each day. One of the most important adverse effects of anticoagulation therapy is life-threatening hemorrhage, and it may result in visits to the emergency department. Some of the common reversal agents include Vitamin K, protamine sulfate, desmopressin, recombinant Factor VIIa, and prothrombin complex concentrates. Each of these agents has the potential to reverse specific anticoagulation therapies, but each agent has a unique administration procedure and monitoring parameters. However, these agents are not without risk of adverse effects. Knowledge of unique aspects of each reversal agent and the anticoagulation therapy must be considered when selecting or recommending pharmacologic anticoagulation reversal therapy. The intent of this review is to discuss the relevant management issues associated with anticoagulant reversal in the emergency department. Copyright © 2011 Wolters Kluwer Health | Lippincott Williams &Wilkins.
First Page
212
Last Page
223
DOI
10.1097/TME.0b013e31822638ae
Publication Date
7-1-2011
Recommended Citation
Lemon, Stephen J. and Crannage, Andrew J., "Pharmacologic anticoagulation reversal in the emergency department" (2011). Pharmacy Practice Faculty Publications. 280.
https://doi.org/10.1097/TME.0b013e31822638ae
https://collections.uhsp.edu/pharm-practice_pubs/280