Pneumonia pathogen characterization is an independent determinant of hospital readmission
Document Type
Article
Publication Title
Chest
Abstract
BACKGROUND: Hospital readmissions for pneumonia occur often and are difficult to predict. For fiscal year 2013, the Centers for Medicare & Medicaid Services readmission penalties have been applied to acute myocardial infarction, heart failure, and pneumonia. However, the overall impact of pneumonia pathogen characterization on hospital readmission is undefined. METHODS: This was a retrospective 6-year cohort study (August 2007 to September 2013). RESULTS: We evaluated 9,624 patients with a discharge diagnosis of pneumonia. Among these patients, 4,432 (46.1%) were classified as having culture-negative pneumonia, 1,940 (20.2%) as having pneumonia caused by antibiotic-susceptible bacteria, 2,991 (31.1%) as having pneumonia caused by potentially antibiotic-resistant bacteria, and 261 (2.7%) as having viral pneumonia. The 90-day hospital readmission rate for survivors (n = 7,637, 79.4%) was greatest for patients with pneumonia attributed to potentially antibiotic-resistant bacteria (11.4%) followed by viral pneumonia (8.3%), pneumonia attributed to antibiotic-susceptible bacteria (6.6%), and culture-negative pneumonia (5.8%) (P<.001). Multiple logistic regression analysis identified pneumonia attributed to potentially antibiotic-resistant bacteria to be independently associated with 90-day readmission (OR, 1.75; 95% CI, 1.56-1.97; P<.001). Other independent predictors of 90-day readmission were Charlson comorbidity score >4, cirrhosis, and chronic kidney disease. Culture-negative pneumonia was independently associated with lower risk for 90-day readmission. CONCLUSIONS: Readmission after hospitalization for pneumonia is relatively common and is related to pneumonia pathogen characterization. Pneumonia attributed to potentially antibiotic-resistant bacteria is associated with an increased risk for 90-day readmission, whereas culture-negative pneumonia is associated with lower risk for 90-day readmission.
First Page
103
Last Page
111
DOI
10.1378/chest.14-2129
Publication Date
7-1-2015
Recommended Citation
Andruska, Adam; Micek, Scott T.; Shindo, Yuichiro; Hampton, Nicholas; Colona, Brian; McCormick, Sandra; and Kollef, Marin H., "Pneumonia pathogen characterization is an independent determinant of hospital readmission" (2015). Pharmacy Practice Faculty Publications. 67.
https://doi.org/10.1378/chest.14-2129
https://collections.uhsp.edu/pharm-practice_pubs/67