Submissions from 2008
In vivo imaging and drug storage by quantum-dot-conjugated carbon nanotubes, Yan Guo, Donglu Shi, Hoonsung Cho, Zhongyun Dong, Amit Kulkarni, Giovanni M. Pauletti, Wei Wang, Jie Lian, Wen Liu, Lei Ren, Qiqing Zhang, Guokui Liu, Christopher Huth, Lumin Wang, and Rodney C. Ewing
The protein kinase A pathway contributes to Hg2+-induced alterations in phosphorylation and subcellular distribution of occludin associated with increased tight junction permeability of salivary epithelial cell monolayers, Jitesh D. Kawedia, Mengmeng Jiang, Amit Kulkarni, Holly E. Waechter, Karl S. Matlin, Giovanni M. Pauletti, and Anil G. Menon
Experimental design comparison of studies evaluating doxorubicin nanoparticles in breast cancer therapy, Farman A. Moayed, Giovanni M. Pauletti, Richard Shell, and Ash Genaidy
Design and synthesis of benzo-lipoxin A4 analogs with enhanced stability and potent anti-inflammatory properties, Nicos A. Petasis, Raquel Keledjian, Yee Ping Sun, Kalyan C. Nagulapalli, Eric Tjonahen, Rong Yang, and Charles N. Serhan
Submissions from 2007
Enaminones: Exploring additional therapeutic activities, Ivan O. Edafiogho, Samuel B. Kombian, Kethireddy V.V. Ananthalakshmi, Noha N. Salama, Natalie D. Eddington, Tiffany L. Wilson, Mariano S. Alexander, Patrice L. Jackson, Clive D. Hanson, and K. R. Scott
Texas community pharmacists' willingness to participate in pharmacist-initiated emergency contraception, Scott K. Griggs and Carolyn M. Brown
Sulfasalazine-induced reduction of glutathione levels in breast cancer cells: Enhancement of growth-inhibitory activity of doxorubicin, Vishal S. Narang, Giovanni M. Pauletti, Peter W. Gout, Donna J. Buckley, and Arthur R. Buckley
Submissions from 2006
Novel mechanisms of G protein-dependent regulation of endothelial nitric-oxide synthase, Alexandra V. Andreeva, Rita Vaiskunaite, Mikhail A. Kutuzov, Jasmina Profirovic, Randal A. Skidgel, and Tatyana Voyno-Yasenetskaya
Docetaxel, cisplatin, and trastuzumab as primary systemic therapy for human epidermal growth factor receptor 2-positive locally advanced breast cancer, Judith Hurley, Philomena Doliny, Isildinha Reis, Orlando Silva, Carmen Gomez-Fernandez, Pedro Velez, Giovanni Pauletti, Mark D. Pegram, and Dennis J. Slamon
Tight junction modulation and its relationship to drug delivery, Noha N. Salama, Natalie D. Eddington, and Alessio Fasano
Recent developments in drug targets and delivery of anti-HIV drugs, Noha N. Salama, Aaron Endsley, and Rodney J.Y. Ho
MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells, Noha N. Salama, Ziping Yang, Tot Bui, and Rodney J.Y. Ho
Submissions from 2005
Gα12 interaction with αSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function, Alexandra V. Andreeva, Mikhail A. Kutuzov, Rita Vaiskunaite, Jasmina Profirovic, Thomas E. Meigs, Sanda Predescu, Asrar B. Malik, and Tatyana Voyno-Yasenetskaya
Nitric oxide mediates increased P-glycoprotein activity in interferon-γ-stimulated human intestinal cells, Santosh G. Dixit, Basilia Zingarelli, Donna J. Buckley, Arthur R. Buckley, and Giovanni M. Pauletti
LIM kinase 1 coordinates microtubule stability and actin polymerization in human endothelial cells, Matvey Gorovoy, Jiaxin Niu, Ora Bernard, Jasmina Profirovic, Richard Minshall, Radu Neamu, and Tatyana Voyno-Yasenetskaya
Design, synthesis and bioactions of novel stable mimetics of lipoxins and aspirin-triggered lipoxins, Nicos A. Petasis, Irini Akritopoulou-Zanze, Valery V. Fokin, Giovanni Bernasconi, Raquel Keledjian, Rong Yang, Jasim Uddin, Kalyan C. Nagulapalli, and Charles N. Serhan
A novel mechanism of G protein-dependent phosphorylation of vasodilator-stimulated phosphoprotein, Jasmina Profirovic, Matvey Gorovoy, Jiaxin Niu, Sasa Pavlovic, and Tatyana Voyno-Yasenetskaya
The impact of ΔG on the oral bioavailability of low bioavailable therapeutic agents, Noha N. Salama, Alessio Fasano, Manjusha Thakar, and Natalie D. Eddington
The impact of pharmacologic and genetic knockout of P-glycoprotein on nelfinavir levels in the brain and other tissues in mice, Noha N. Salama, Edward J. Kelly, Tot Bui, and Rodney J.Y. Ho
Submissions from 2004
HER-2/neu gene amplification and response to paclitaxel in patients with metastatic breast cancer, Gottfried E. Konecny, Christoph Thomssen, Hans Joachim Lück, Michael Untch, He Jing Wang, Walter Kuhn, Holger Eidtmann, Andreas du Bois, Sigrid Olbricht, Dieter Steinfeld, Volker Möbus, Gunter von Minckwitz, Suganda Dandekar, Lilian Ramos, Giovanni Pauletti, Mark D. Pegram, Fritz Jänicke, and Dennis J. Slamon
Multidrug resistance and anticonvulsants: New studies with some enaminones, Noha Nabil Salama, Natalie D. Eddington, Debra Payne, Tiffany L. Wilson, and K. R. Scott
The Effect of ΔG on the Transport and Oral Absorption of Macromolecules, Noha N. Salama, Alessio Fasano, Manjusha Thakar, and Natalie D. Eddington
DM27, an enaminone, modifies the in vitro transport of antiviral therapeutic agents, Noha N. Salama, Kenneth R. Scott, and Natalie D. Eddington
The influence of enaminones on the transport and oral bioavailability of P-glycoprotein substrate therapeutic agents, Noha N. Salama, Kenneth R. Scott, and Natalie D. Eddington
Submissions from 2003
Extracellular glucose concentration alters functional activity of the intestinal oligopeptide transporter (PepT-1) in Caco-2 cells, Vanessa M. D'Souza, Donna J. Buckley, Arthur R. Buckley, and Giovanni M. Pauletti
High glucose concentration in isotonic media alters Caco-2 cell permeability, Vanessa M. D'Souza, Howard G. Shertzer, Anil G. Menon, and Giovanni M. Pauletti
High glucose concentration in isotonic media alters Caco-2 cell permeability, Vanessa M. D'Souza, Howard G. Shertzer, Anil G. Menon, and Giovanni M. Pauletti
Synthesis and anticonvulsant activity of enaminones - Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives, Natalie D. Eddington, Donna S. Cox, Manoj Khurana, Noha N. Salama, James P. Stables, Sylvia J. Harrison, Abraham Negussie, Robert S. Taylor, Uy Q. Tran, Jacqueline A. Moore, Judith C. Barrow, and K. R. Scott
Preclinical evaluation of the pharmacokinetics, brain uptake and metabolism of E121, an antiepileptic enaminone ester, in rats, Manoj Khurana, Noha N. Salama, Kenneth R. Scott, Noble N. Nemieboka, Kenneth S. Bauer, and Natalie D. Eddington
A novel 2:1 cycloadduct of dimethyl acetylenedicarboxylate with 3,5-diphenyl-4-methoximino-4H-pyrazole 1,2-dioxide, Andre L. Kilpatrick, Kalyan Nagulapalli, Joel M. Esken, Gregory M. Ferrence, and John F. Hansen
Quantitative association between HER-2/neu and steroid hormone receptors in hormone receptor-positive primary breast cancer, Gottfried Konecny, Giovanni Pauletti, Mark Pegram, Michael Untch, Sugandha Dandekar, Zuleima Aguilar, Cindy Wilson, Hong Mei Rong, Ingo Bauerfeind, Margret Felber, He Jing Wang, Malgorzata Beryt, Ram Seshadri, Herrmann Hepp, and Dennis J. Slamon
Suppression of Cystine Uptake by Sulfasalazine Inhibits Proliferation of Human Mammary Carcinoma Cells, Vishal S. Narang, Giovanni M. Pauletti, Peter W. Gout, Donna J. Buckley, and Arthur R. Buckley
G Protein βγ Subunits Stimulate p114RhoGEF, a Guanine Nucleotide Exchange Factor for RhoA and Rac1: Regulation of Cell Shape and Reactive Oxygen Species Production, Jiaxin Niu, Jasmina Profirovic, Haiyun Pan, Rita Vaiskunaite, and Tatyana Voyno-Yasenetskaya
Effect of the biologically active fragment of zonula occludens toxin, ΔG, on the intestinal paracellular transport and oral absorption of mannitol, Noha N. Salama, Alessio Fasano, Ruliang Lu, and Natalie D. Eddington
Submissions from 2002
Enhanced permeability of molecular weight markers and poorly bioavailable compounds across Caco-2 cell monolayers using the absorption enhancer, zonula occludens toxin, Donna S. Cox, Sangeeta Raje, Huanling Gao, Noha N. Salama, and Natalie D. Eddington
Cyclin D1 amplification and pl6(MTS1/CDK4I) deletion correlate with poor prognosis in head and neck tumors, Ali Namazie, Sassan Alavi, Olufunmilayo I. Olopade, Giovanni Pauletti, Neema Aghamohammadi, M. Aghamohammadi, Jeffrey A. Gornbein, Thomas C. Calcaterra, Dennis J. Slamon, Marilene B. Wang, and Eri S. Srivatsan
Characterization of acetylcholinesterase in Caco-2 cells, Lauren R. Plageman, Giovanni M. Pauletti, and Kenneth A. Skau
5-Hydroxytryptamine 4(a) receptor is coupled to the Gα subunit of heterotrimeric G13 protein, Evgeni G. Ponimaskin, Jasmina Profirovic, Rita Vaiskunaite, Diethelm W. Richter, and Tatyana A. Voyno-Yasenetskaya
Submissions from 2000
Assessment of methods for tissue-based detection of the HER-2/neu alteration in human breast cancer: A direct comparison of fluorescence in situ hybridization and immunohistochemistry, Giovanni Pauletti, Suganda Dandekar, Hong Mei Rong, Lilllian Ramos, Hong Jun Peng, Ram Seshadri, and Dennis J. Slamon
Submissions from 1999
Coumarinic acid-based cyclic prodrugs of opioid peptides that exhibit metabolic stability to peptidases and excellent cellular permeability, Olafur S. Gudmundsson, Giovanni M. Pauletti, Wei Wang, Daxian Shan, Huijuan Zhang, Binghe Wang, and Ronald T. Borchardt
Submissions from 1998
HER-2/neu as a predictive marker of response to breast cancer therapy, Mark D. Pegram, Giovanni Pauletti, and Dennis J. Slamon
Transport characteristics of peptidomimetics. Effect of the pyrrolinone bioisostere on transport across Caco-2 cell monolayers, Masao Sudoh, Giovanni M. Pauletti, Wenqing Yao, William Moser, Akihisa Yokoyama, Alexander Pasternak, Paul A. Sprengeler, Amos B. Smith, Ralph Hirschmann, and Ronald T. Borchardt
Submissions from 1997
Synthesis of a novel esterase-sensitive cyclic prodrug of a hexapeptide using an (acyloxy)alkoxy promoiety, Sanjeev Gangwar, Giovanni M. Pauletti, Teruna J. Siahaan, Valentino J. Stella, and Ronald T. Borchardt
Novel esterase-sensitive cyclic prodrugs of a model hexapeptide having enhanced membrane permeability and enzymatic stability, Sanjeev Gangwar, Giovanni M. Pauletti, Binghe Wang, Teruna J. Siahaan, Valentino J. Stella, and Ronald T. Borchardt
Prodrug strategies to enhance the intestinal absorption of peptides, Sanjeev Gangwar, Giovanni M. Pauletti, Binghe Wang, Teruna J. Siahaan, Valentino J. Stella, and Ronald T. Borchardt
Effect of restricted conformational flexibility on the permeation of model hexapeptides across caco-2 cell monolayers, Franklin W. Okumu, Giovanni M. Pauletti, David G. Vander Velde, Teruna J. Siahaan, and Ronald T. Borchardt
Improvement of oral peptide bioavailability: Peptidomimetics and prodrug strategies, Giovanni M. Pauletti, Sanjeev Gangwar, Teruna J. Siahaan, Jeffrey Aubé, and Ronald T. Borchardt
Esterase-sensitive cyclic prodrugs of peptides: Evaluation of a phenylpropionic acid promoiety in a model hexapeptide, Giovanni M. Pauletti, Sanjeev Gangwar, Binghe Wang, and Ronald T. Borchardt
Effect of size and charge on the, passive diffusion of peptides across caco-2 cell monolayers via the paracellular pathway, Giovanni M. Pauletti, Franklin W. Okumu, and Ronald T. Borchardt
Synthesis of a Novel Esterase-Sensitive Cyclic Prodrug System for Peptides That Utilizes a "Trimethyl Lock"-Facilitated Lactonization Reaction, Binghe Wang, Sanjeev Gangwar, Giovanni M. Pauletti, Teruna J. Siahaan, and Ronald T. Borchardt
Submissions from 1996
Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization, Giovanni Pauletti, William Godolphin, Michael F. Press, and Dennis J. Slamon
Structural requirements for intestinal absorption of peptide drugs, Giovanni M. Pauletti, Sanjeev Gangwar, Gregory T. Knipp, Manoj M. Nerurkar, Franklin W. Okumu, Kiyoshi Tamura, Teruna J. Siahaan, and Ronald T. Borchardt
Esterase-sensitive cyclic prodrugs of peptides: Evaluation of an acyloxyalkoxy promoiety in a model hexapeptide, Giovanni M. Pauletti, Sanjeev Gangwar, Franklin W. Okumu, Teruna J. Siahaan, Valentino J. Stella, and Ronald T. Borchardt
Submissions from 1994
Artificial membranes as standardised distribution models, St Kramer, G. M. Pauletti, and H. Wunderli-Allenspach
Partition coefficients in vitro: artificial membranes as a standardized distribution model, Giovanni M. Pauletti and Heidi Wunderli-Allenspach
Submissions from 1990
Early appearance and long-term persistence of the submicroscopic extrachromosomal elements (amplisomes) containing the amplified DHFR genes in human cell lines, Giovanni Pauletti, Eric Lai, and Giuseppe Attardi